Cargando…

Diagnoses Based on C-Reactive Protein Point-of-Care Tests

C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory metho...

Descripción completa

Detalles Bibliográficos
Autor principal: Pohanka, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138282/
https://www.ncbi.nlm.nih.gov/pubmed/35624645
http://dx.doi.org/10.3390/bios12050344
_version_ 1784714586220396544
author Pohanka, Miroslav
author_facet Pohanka, Miroslav
author_sort Pohanka, Miroslav
collection PubMed
description C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory methods and simple point-of-care devices such as lateral flow tests and immunoturbidimetric assays serve for the instrumental diagnoses based on CRP. The current method for CRP has many flaws and limitations in its use. Biosensor and bioassay analytical devices are presently researched by many teams to provide more sensitive and better-suited tools for point-of-care tests of CRP in biological samples when compared to the standard methods. This review article is focused on mapping the diagnostical relevance of CRP, the applicability of the current analytical methods, and the recent innovations in the measurement of CRP level.
format Online
Article
Text
id pubmed-9138282
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91382822022-05-28 Diagnoses Based on C-Reactive Protein Point-of-Care Tests Pohanka, Miroslav Biosensors (Basel) Review C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory methods and simple point-of-care devices such as lateral flow tests and immunoturbidimetric assays serve for the instrumental diagnoses based on CRP. The current method for CRP has many flaws and limitations in its use. Biosensor and bioassay analytical devices are presently researched by many teams to provide more sensitive and better-suited tools for point-of-care tests of CRP in biological samples when compared to the standard methods. This review article is focused on mapping the diagnostical relevance of CRP, the applicability of the current analytical methods, and the recent innovations in the measurement of CRP level. MDPI 2022-05-17 /pmc/articles/PMC9138282/ /pubmed/35624645 http://dx.doi.org/10.3390/bios12050344 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pohanka, Miroslav
Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title_full Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title_fullStr Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title_full_unstemmed Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title_short Diagnoses Based on C-Reactive Protein Point-of-Care Tests
title_sort diagnoses based on c-reactive protein point-of-care tests
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138282/
https://www.ncbi.nlm.nih.gov/pubmed/35624645
http://dx.doi.org/10.3390/bios12050344
work_keys_str_mv AT pohankamiroslav diagnosesbasedoncreactiveproteinpointofcaretests