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Diagnoses Based on C-Reactive Protein Point-of-Care Tests
C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory metho...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138282/ https://www.ncbi.nlm.nih.gov/pubmed/35624645 http://dx.doi.org/10.3390/bios12050344 |
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author | Pohanka, Miroslav |
author_facet | Pohanka, Miroslav |
author_sort | Pohanka, Miroslav |
collection | PubMed |
description | C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory methods and simple point-of-care devices such as lateral flow tests and immunoturbidimetric assays serve for the instrumental diagnoses based on CRP. The current method for CRP has many flaws and limitations in its use. Biosensor and bioassay analytical devices are presently researched by many teams to provide more sensitive and better-suited tools for point-of-care tests of CRP in biological samples when compared to the standard methods. This review article is focused on mapping the diagnostical relevance of CRP, the applicability of the current analytical methods, and the recent innovations in the measurement of CRP level. |
format | Online Article Text |
id | pubmed-9138282 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91382822022-05-28 Diagnoses Based on C-Reactive Protein Point-of-Care Tests Pohanka, Miroslav Biosensors (Basel) Review C-reactive protein (CRP) is an important part of the immune system’s reaction to various pathological impulses such as bacterial infections, systemic inflammation, and internal organ failures. An increased CRP level serves to diagnose the mentioned pathological states. Both standard laboratory methods and simple point-of-care devices such as lateral flow tests and immunoturbidimetric assays serve for the instrumental diagnoses based on CRP. The current method for CRP has many flaws and limitations in its use. Biosensor and bioassay analytical devices are presently researched by many teams to provide more sensitive and better-suited tools for point-of-care tests of CRP in biological samples when compared to the standard methods. This review article is focused on mapping the diagnostical relevance of CRP, the applicability of the current analytical methods, and the recent innovations in the measurement of CRP level. MDPI 2022-05-17 /pmc/articles/PMC9138282/ /pubmed/35624645 http://dx.doi.org/10.3390/bios12050344 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pohanka, Miroslav Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title | Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title_full | Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title_fullStr | Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title_full_unstemmed | Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title_short | Diagnoses Based on C-Reactive Protein Point-of-Care Tests |
title_sort | diagnoses based on c-reactive protein point-of-care tests |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138282/ https://www.ncbi.nlm.nih.gov/pubmed/35624645 http://dx.doi.org/10.3390/bios12050344 |
work_keys_str_mv | AT pohankamiroslav diagnosesbasedoncreactiveproteinpointofcaretests |