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Dyskerin Downregulation Can Induce ER Stress and Promote Autophagy via AKT-mTOR Signaling Deregulation

Dyskerin is an evolutionarily conserved nucleolar protein implicated in a wide range of fundamental biological roles, including telomere maintenance and ribosome biogenesis. Germline mutations of DKC1, the human gene encoding dyskerin, cause the hereditary disorders known as X-linked dyskeratosis co...

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Detalles Bibliográficos
Autores principales:	Maiello, Daniela, Varone, Marianna, Vicidomini, Rosario, Belli, Valentina, De Rosa, Marina, Dama, Paola, Furia, Maria, Turano, Mimmo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138296/ https://www.ncbi.nlm.nih.gov/pubmed/35625829 http://dx.doi.org/10.3390/biomedicines10051092

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