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The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis

Transforming growth factor β (TGF-β) is a multifunctional cytokine regulating homeostasis and immune responses in adult animals and humans. Aberrant and overactive TGF-β signaling promotes cancer initiation and fibrosis through epithelial–mesenchymal transition (EMT), as well as the invasion and met...

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Detalles Bibliográficos
Autores principales: Mallikarjuna, Pramod, Zhou, Yang, Landström, Maréne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138354/
https://www.ncbi.nlm.nih.gov/pubmed/35625561
http://dx.doi.org/10.3390/biom12050635