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The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis
Transforming growth factor β (TGF-β) is a multifunctional cytokine regulating homeostasis and immune responses in adult animals and humans. Aberrant and overactive TGF-β signaling promotes cancer initiation and fibrosis through epithelial–mesenchymal transition (EMT), as well as the invasion and met...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138354/ https://www.ncbi.nlm.nih.gov/pubmed/35625561 http://dx.doi.org/10.3390/biom12050635 |