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G-Quadruplex-Binding Proteins: Promising Targets for Drug Design

G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5′ non-coding regions, indicating they fulfill important genome regulatory functions. Generally, G4s...

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Detalles Bibliográficos
Autores principales: Shu, Huiling, Zhang, Rongxin, Xiao, Ke, Yang, Jing, Sun, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138358/
https://www.ncbi.nlm.nih.gov/pubmed/35625576
http://dx.doi.org/10.3390/biom12050648

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