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Obesogens in Foods

Obesogens, as environmental endocrine-disrupting chemicals, are supposed to have had an impact on the prevalence of rising obesity around the world over the last forty years. These chemicals are probably able to contribute not only to the development of obesity and metabolic disturbances in individu...

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Autores principales: Kladnicka, Iva, Bludovska, Monika, Plavinova, Iveta, Muller, Ludek, Mullerova, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138445/
https://www.ncbi.nlm.nih.gov/pubmed/35625608
http://dx.doi.org/10.3390/biom12050680
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author Kladnicka, Iva
Bludovska, Monika
Plavinova, Iveta
Muller, Ludek
Mullerova, Dana
author_facet Kladnicka, Iva
Bludovska, Monika
Plavinova, Iveta
Muller, Ludek
Mullerova, Dana
author_sort Kladnicka, Iva
collection PubMed
description Obesogens, as environmental endocrine-disrupting chemicals, are supposed to have had an impact on the prevalence of rising obesity around the world over the last forty years. These chemicals are probably able to contribute not only to the development of obesity and metabolic disturbances in individuals, but also in their progeny, having the capability to epigenetically reprogram genetically inherited set-up points for body weight and body composition control during critical periods of development, such as fetal, early life, and puberty. In individuals, they may act on myriads of neuro-endocrine–immune metabolic regulatory pathways, leading to pathophysiological consequences in adipogenesis, lipogenesis, lipolysis, immunity, the influencing of central appetite and energy expenditure regulations, changes in gut microbiota–intestine functioning, and many other processes. Evidence-based medical data have recently brought much more convincing data about associations of particular chemicals and the probability of the raised risk of developing obesity. Foods are the main source of obesogens. Some obesogens occur naturally in food, but most are environmental chemicals, entering food as a foreign substance, whether in the form of contaminants or additives, and they are used in a large amount in highly processed food. This review article contributes to a better overview of obesogens, their occurrence in foods, and their impact on the human organism.
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spelling pubmed-91384452022-05-28 Obesogens in Foods Kladnicka, Iva Bludovska, Monika Plavinova, Iveta Muller, Ludek Mullerova, Dana Biomolecules Review Obesogens, as environmental endocrine-disrupting chemicals, are supposed to have had an impact on the prevalence of rising obesity around the world over the last forty years. These chemicals are probably able to contribute not only to the development of obesity and metabolic disturbances in individuals, but also in their progeny, having the capability to epigenetically reprogram genetically inherited set-up points for body weight and body composition control during critical periods of development, such as fetal, early life, and puberty. In individuals, they may act on myriads of neuro-endocrine–immune metabolic regulatory pathways, leading to pathophysiological consequences in adipogenesis, lipogenesis, lipolysis, immunity, the influencing of central appetite and energy expenditure regulations, changes in gut microbiota–intestine functioning, and many other processes. Evidence-based medical data have recently brought much more convincing data about associations of particular chemicals and the probability of the raised risk of developing obesity. Foods are the main source of obesogens. Some obesogens occur naturally in food, but most are environmental chemicals, entering food as a foreign substance, whether in the form of contaminants or additives, and they are used in a large amount in highly processed food. This review article contributes to a better overview of obesogens, their occurrence in foods, and their impact on the human organism. MDPI 2022-05-09 /pmc/articles/PMC9138445/ /pubmed/35625608 http://dx.doi.org/10.3390/biom12050680 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kladnicka, Iva
Bludovska, Monika
Plavinova, Iveta
Muller, Ludek
Mullerova, Dana
Obesogens in Foods
title Obesogens in Foods
title_full Obesogens in Foods
title_fullStr Obesogens in Foods
title_full_unstemmed Obesogens in Foods
title_short Obesogens in Foods
title_sort obesogens in foods
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138445/
https://www.ncbi.nlm.nih.gov/pubmed/35625608
http://dx.doi.org/10.3390/biom12050680
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