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The STING Ligand and Delivery System Synergistically Enhance the Immunogenicity of an Intranasal Spike SARS-CoV-2 Vaccine Candidate

The respiratory organ serves as a primary target site for SARS-CoV-2. Thus, the vaccine-stimulating immune response of the respiratory tract is significant in controlling SARS-CoV-2 transmission and disease development. In this study, mucoadhesive nanoparticles were used to deliver SARS-CoV-2 spike...

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Detalles Bibliográficos
Autores principales: Jearanaiwitayakul, Tuksin, Limthongkul, Jitra, Kaofai, Chernkhwan, Apichirapokey, Suttikarn, Chawengkirttikul, Runglawan, Sapsutthipas, Sompong, Sunintaboon, Panya, Ubol, Sukathida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138454/
https://www.ncbi.nlm.nih.gov/pubmed/35625879
http://dx.doi.org/10.3390/biomedicines10051142