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Conformational Entropy as a Potential Liability of Computationally Designed Antibodies
In silico antibody discovery is emerging as a viable alternative to traditional in vivo and in vitro approaches. Many challenges, however, remain open to enabling the properties of designed antibodies to match those produced by the immune system. A major question concerns the structural features of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138470/ https://www.ncbi.nlm.nih.gov/pubmed/35625644 http://dx.doi.org/10.3390/biom12050718 |