Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma

Despite the addition of several new agents to the armamentarium for the treatment of multiple myeloma (MM) in the last decade and improvements in outcomes, the refractory and relapsing disease continues to take a great toll, limiting overall survival. Therefore, additional novel approaches are neede...

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Detalles Bibliográficos
Autores principales: Njomen, Evert, Vanecek, Allison, Lansdell, Theresa A., Yang, Ya-Ting, Schall, Peter Z., Harris, Christi M., Bernard, Matthew P., Isaac, Daniel, Alkharabsheh, Omar, Al-Janadi, Anas, Giletto, Matthew B., Ellsworth, Edmund, Taylor, Catherine, Tang, Terence, Lau, Sarah, Bailie, Marc, Bernard, Jamie J., Yuzbasiyan-Gurkan, Vilma, Tepe, Jetze J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138505/
https://www.ncbi.nlm.nih.gov/pubmed/35625675
http://dx.doi.org/10.3390/biomedicines10050938

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