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Strategy to Enhance Anticancer Activity and Induced Immunogenic Cell Death of Antimicrobial Peptides by Using Non-Nature Amino Acid Substitutions

There is an urgent and imminent need to develop new agents to fight against cancer. In addition to the antimicrobial and anti-inflammatory activities, many antimicrobial peptides can bind to and lyse cancer cells. P-113, a 12-amino acid clinically active histatin-rich peptide, was found to possess a...

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Detalles Bibliográficos
Autores principales: Cheah, Yu-Huan, Liu, Chun-Yu, Yip, Bak-Sau, Wu, Chih-Lung, Peng, Kuang-Li, Cheng, Jya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138567/
https://www.ncbi.nlm.nih.gov/pubmed/35625834
http://dx.doi.org/10.3390/biomedicines10051097