Empagliflozin Reduces the Progression of Hepatic Fibrosis in a Mouse Model and Inhibits the Activation of Hepatic Stellate Cells via the Hippo Signalling Pathway

Hepatic fibrosis is the excessive production and deposition of the extracellular matrix, resulting in the activation of the fibrogenic phenotype of hepatic stellate cells (HSCs). The Hippo/Yes-associated protein (YAP) signalling pathway is a highly conserved kinase cascade that is critical in regula...

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Detalles Bibliográficos
Autores principales: Heo, Yu-Jung, Lee, Nami, Choi, Sung-E, Jeon, Ja-Young, Han, Seung-Jin, Kim, Dae-Jung, Kang, Yup, Lee, Kwan-Woo, Kim, Hae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138578/
https://www.ncbi.nlm.nih.gov/pubmed/35625768
http://dx.doi.org/10.3390/biomedicines10051032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138578/
https://www.ncbi.nlm.nih.gov/pubmed/35625768
http://dx.doi.org/10.3390/biomedicines10051032

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