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Empagliflozin Reduces the Progression of Hepatic Fibrosis in a Mouse Model and Inhibits the Activation of Hepatic Stellate Cells via the Hippo Signalling Pathway
Hepatic fibrosis is the excessive production and deposition of the extracellular matrix, resulting in the activation of the fibrogenic phenotype of hepatic stellate cells (HSCs). The Hippo/Yes-associated protein (YAP) signalling pathway is a highly conserved kinase cascade that is critical in regula...
Autores principales: | Heo, Yu-Jung, Lee, Nami, Choi, Sung-E, Jeon, Ja-Young, Han, Seung-Jin, Kim, Dae-Jung, Kang, Yup, Lee, Kwan-Woo, Kim, Hae-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138578/ https://www.ncbi.nlm.nih.gov/pubmed/35625768 http://dx.doi.org/10.3390/biomedicines10051032 |
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