Cargando…

Potential and Therapeutic Roles of Diosmin in Human Diseases

Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade. Plants contain a huge number of flavonoids, and Diosmin, a flavone glycoside, is one of them. Numerous in-vitr...

Descripción completa

Detalles Bibliográficos
Autores principales: Huwait, Etimad, Mobashir, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138579/
https://www.ncbi.nlm.nih.gov/pubmed/35625813
http://dx.doi.org/10.3390/biomedicines10051076
_version_ 1784714656887078912
author Huwait, Etimad
Mobashir, Mohammad
author_facet Huwait, Etimad
Mobashir, Mohammad
author_sort Huwait, Etimad
collection PubMed
description Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade. Plants contain a huge number of flavonoids, and Diosmin, a flavone glycoside, is one of them. Numerous in-vitro and in-vivo studies have validated Diosmin’s extensive range of biological capabilities which present antioxidative, antihyperglycemic, anti-inflammatory, antimutagenic, and antiulcer properties. We have presented this review work because of the greater biological properties and influences of Diosmin. We have provided a brief overview of Diosmin, its pharmacology, major biological properties, such as anti-cancer, anti-diabetic, antibacterial, anticardiovascular, liver protection, and neuroprotection, therapeutic approach, potential Diosmin targets, and pathways that are known to be associated with it.
format Online
Article
Text
id pubmed-9138579
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91385792022-05-28 Potential and Therapeutic Roles of Diosmin in Human Diseases Huwait, Etimad Mobashir, Mohammad Biomedicines Review Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade. Plants contain a huge number of flavonoids, and Diosmin, a flavone glycoside, is one of them. Numerous in-vitro and in-vivo studies have validated Diosmin’s extensive range of biological capabilities which present antioxidative, antihyperglycemic, anti-inflammatory, antimutagenic, and antiulcer properties. We have presented this review work because of the greater biological properties and influences of Diosmin. We have provided a brief overview of Diosmin, its pharmacology, major biological properties, such as anti-cancer, anti-diabetic, antibacterial, anticardiovascular, liver protection, and neuroprotection, therapeutic approach, potential Diosmin targets, and pathways that are known to be associated with it. MDPI 2022-05-06 /pmc/articles/PMC9138579/ /pubmed/35625813 http://dx.doi.org/10.3390/biomedicines10051076 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huwait, Etimad
Mobashir, Mohammad
Potential and Therapeutic Roles of Diosmin in Human Diseases
title Potential and Therapeutic Roles of Diosmin in Human Diseases
title_full Potential and Therapeutic Roles of Diosmin in Human Diseases
title_fullStr Potential and Therapeutic Roles of Diosmin in Human Diseases
title_full_unstemmed Potential and Therapeutic Roles of Diosmin in Human Diseases
title_short Potential and Therapeutic Roles of Diosmin in Human Diseases
title_sort potential and therapeutic roles of diosmin in human diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138579/
https://www.ncbi.nlm.nih.gov/pubmed/35625813
http://dx.doi.org/10.3390/biomedicines10051076
work_keys_str_mv AT huwaitetimad potentialandtherapeuticrolesofdiosmininhumandiseases
AT mobashirmohammad potentialandtherapeuticrolesofdiosmininhumandiseases