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The Metabolic Activation of Sofosbuvir Is Impaired in an Experimental Model of NAFLD

SIMPLE SUMMARY: Steatosis is a disease of the liver characterized by the deposition of lipids in hepatocytes. Although the effect of steatosis on the metabolism of drugs has been investigated, the findings obtained so far are still controversial. We here evaluated the pharmacokinetics of the main in...

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Detalles Bibliográficos
Autores principales:	Gabbia, Daniela, Roverso, Marco, Sarcognato, Samantha, Zanotto, Ilaria, Ferri, Nicola, Russo, Francesco Paolo, Guido, Maria, Bogialli, Sara, De Martin, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138586/ https://www.ncbi.nlm.nih.gov/pubmed/35625421 http://dx.doi.org/10.3390/biology11050693

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