Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

The HIV-1 capsid (CA) protein has emerged as an attractive therapeutic target. However, all inhibitor designs and structural analyses for this essential HIV-1 protein have focused on the clade B HIV-1 (NL4-3) variant. This study creates, overproduces, purifies, and characterizes the CA proteins from...

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Detalles Bibliográficos
Autores principales: Dick, Alexej, Meuser, Megan E., Cocklin, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138599/
https://www.ncbi.nlm.nih.gov/pubmed/35625621
http://dx.doi.org/10.3390/biom12050695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138599/
https://www.ncbi.nlm.nih.gov/pubmed/35625621
http://dx.doi.org/10.3390/biom12050695

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