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Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

The HIV-1 capsid (CA) protein has emerged as an attractive therapeutic target. However, all inhibitor designs and structural analyses for this essential HIV-1 protein have focused on the clade B HIV-1 (NL4-3) variant. This study creates, overproduces, purifies, and characterizes the CA proteins from...

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Detalles Bibliográficos
Autores principales:	Dick, Alexej, Meuser, Megan E., Cocklin, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138599/ https://www.ncbi.nlm.nih.gov/pubmed/35625621 http://dx.doi.org/10.3390/biom12050695

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