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Alanine–Glyoxylate Aminotransferase Sustains Cancer Stemness Properties through the Upregulation of SOX2 and OCT4 in Hepatocellular Carcinoma Cells

Liver cancer stem cells (LCSCs) are a small subset of oncogenic cells with a self-renewal ability and drug resistance, and they promote the recurrence and metastasis of hepatocellular carcinoma (HCC). However, the mechanisms regulating LCSCs have not been fully explored. By enriching LCSCs from sphe...

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Detalles Bibliográficos
Autores principales: Ye, Peng, Chi, Xiaoxia, Yan, Xiuwen, Wu, Fangqin, Liang, Zhigang, Yang, Wen-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138635/
https://www.ncbi.nlm.nih.gov/pubmed/35625596
http://dx.doi.org/10.3390/biom12050668