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Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease

Background: Patients with chronic obstructive pulmonary disease (COPD) are commonly treated with inhaled corticosteroid/long-acting ß2-agonist combination therapy. While previous studies have investigated the host–microbiome interactions in COPD, the effects of specific steroid formulations on this...

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Detalles Bibliográficos
Autores principales: Yip, William, Li, Xuan, Koelwyn, Graeme J., Milne, Stephen, Leitao Filho, Fernando Sergio, Yang, Chen Xi, Hernández Cordero, Ana I., Yang, Julia, Yang, Cheng Wei Tony, Shaipanich, Tawimas, van Eeden, Stephan F., Leung, Janice M., Lam, Stephen, McNagny, Kelly M., Sin, Don D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138653/
https://www.ncbi.nlm.nih.gov/pubmed/35625847
http://dx.doi.org/10.3390/biomedicines10051110