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Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of APC and β-Catenin Mutational Status

Colorectal cancer (CRC) pathogenesis is mainly driven by alterations in WNT signaling, which results in altered transcriptional activity of β-Catenin. Mutations in APC (Adenomatous Polyposis Coli) are reflected in β-Catenin hyperactivation and loss of proliferation control. Certain intestinal bacter...

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Detalles Bibliográficos
Autores principales:	Garavaglia, Beatrice, Vallino, Letizia, Ferraresi, Alessandra, Esposito, Andrea, Salwa, Amreen, Vidoni, Chiara, Gentilli, Sergio, Isidoro, Ciro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138675/ https://www.ncbi.nlm.nih.gov/pubmed/35625868 http://dx.doi.org/10.3390/biomedicines10051131

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