Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer

Breast cancer is the most prevalent malignancy among women worldwide and hereditary breast cancer (HBC) accounts for about 5–10% of the cases. Today, the most recurrent genes known are BRCA1 and BRCA2, accounting for around 25% of familial cases. Although thousands of loss-of-function variants in mo...

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Detalles Bibliográficos
Autores principales: Liu, Yaxuan, Helgadottir, Hafdis T., Kharaziha, Pedram, Choi, Jungmin, López-Giráldez, Francesc, Mane, Shrikant M., Höiom, Veronica, Juhlin, Carl Christofer, Larsson, Catharina, Bajalica-Lagercrantz, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138793/
https://www.ncbi.nlm.nih.gov/pubmed/35625741
http://dx.doi.org/10.3390/biomedicines10051004

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