Multiple Mutations in the Non-Ordered Red Ω-Loop Enhance the Membrane-Permeabilizing and Peroxidase-like Activity of Cytochrome c

A key event in the cytochrome c-dependent apoptotic pathway is the permeabilization of the outer mitochondrial membrane, resulting in the release of various apoptogenic factors, including cytochrome c, into the cytosol. It is believed that the permeabilization of the outer mitochondrial membrane can...

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Detalles Bibliográficos
Autores principales: Chertkova, Rita V., Firsov, Alexander M., Brazhe, Nadezda A., Nikelshparg, Evelina I., Bochkova, Zhanna V., Bryantseva, Tatyana V., Semenova, Marina A., Baizhumanov, Adil A., Kotova, Elena A., Kirpichnikov, Mikhail P., Maksimov, Georgy V., Antonenko, Yuriy N., Dolgikh, Dmitry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138828/
https://www.ncbi.nlm.nih.gov/pubmed/35625593
http://dx.doi.org/10.3390/biom12050665

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