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The Use of Machine Learning Algorithms and the Mass Spectrometry Lipidomic Profile of Serum for the Evaluation of Tacrolimus Exposure and Toxicity in Kidney Transplant Recipients

Tacrolimus has a narrow therapeutic window; a whole-blood trough target concentration of between 5 and 8 ng/mL is considered a safe level for stable kidney transplant recipients. Tacrolimus serum levels must be closely monitored to obtain a balance between maximizing efficacy and minimizing dose-rel...

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Detalles Bibliográficos
Autores principales:	Burghelea, Dan, Moisoiu, Tudor, Ivan, Cristina, Elec, Alina, Munteanu, Adriana, Iancu, Ștefania D., Truta, Anamaria, Kacso, Teodor Paul, Antal, Oana, Socaciu, Carmen, Elec, Florin Ioan, Kacso, Ina Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138871/ https://www.ncbi.nlm.nih.gov/pubmed/35625894 http://dx.doi.org/10.3390/biomedicines10051157

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