Intranasal Administration of a TRAIL Neutralizing Monoclonal Antibody Adsorbed in PLGA Nanoparticles and NLC Nanosystems: An In Vivo Study on a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that progressively compromises cognitive functions. Tumor necrosis factor (TNF)-Related Apoptosis Inducing Ligand (TRAIL), a proinflammatory cytokine belonging to the TNF superfamily, appears to be a key player in the inflammatory/immune orche...

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Detalles Bibliográficos
Autores principales: Musumeci, Teresa, Di Benedetto, Giulia, Carbone, Claudia, Bonaccorso, Angela, Amato, Giovanni, Lo Faro, Maria Josè, Burgaletto, Chiara, Puglisi, Giovanni, Bernardini, Renato, Cantarella, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138905/
https://www.ncbi.nlm.nih.gov/pubmed/35625722
http://dx.doi.org/10.3390/biomedicines10050985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138905/
https://www.ncbi.nlm.nih.gov/pubmed/35625722
http://dx.doi.org/10.3390/biomedicines10050985

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