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Prevention of hepatocellular carcinoma and monitoring of high-risk patients

Hepatocellular carcinoma (HCC) accounts for some 80% of primary liver tumors. According to recent data, HCC is the sixth most common type of cancer and the third leading cause of cancer-related mortality worldwide. Risk factors for HCC include the presence of the hepatitis B virus, hepatitis C virus...

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Autores principales: Kaya, Eda, Daniel Mazzolini, Guillermo, Yilmaz, Yusuf, Canbay, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138915/
https://www.ncbi.nlm.nih.gov/pubmed/35782375
http://dx.doi.org/10.14744/hf.2021.2021.0033
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author Kaya, Eda
Daniel Mazzolini, Guillermo
Yilmaz, Yusuf
Canbay, Ali
author_facet Kaya, Eda
Daniel Mazzolini, Guillermo
Yilmaz, Yusuf
Canbay, Ali
author_sort Kaya, Eda
collection PubMed
description Hepatocellular carcinoma (HCC) accounts for some 80% of primary liver tumors. According to recent data, HCC is the sixth most common type of cancer and the third leading cause of cancer-related mortality worldwide. Risk factors for HCC include the presence of the hepatitis B virus, hepatitis C virus, non-alcoholic fatty liver disease, and exposure to noxious agents, such as alcohol, or toxins, such as aflatoxin, which are considered preventable etiologies of HCC. Monitoring strategies are needed for patients at risk of developing HCC. There is a consensus on routine monitoring of cirrhotic patients due to definitive evidence of a significantly high rate of progression to HCC; however, the appropriate surveillance of patients with advanced fibrosis remains a topic of discussion. Nevertheless, adherence to a strict observation protocol is the cornerstone of early detection and treatment with curative options for patients with a high risk of developing HCC. This review examines prevention strategies, risk factors, and surveillance based on current guidelines.
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spelling pubmed-91389152022-07-01 Prevention of hepatocellular carcinoma and monitoring of high-risk patients Kaya, Eda Daniel Mazzolini, Guillermo Yilmaz, Yusuf Canbay, Ali Hepatol Forum Review - HCC prevention and surveillance Hepatocellular carcinoma (HCC) accounts for some 80% of primary liver tumors. According to recent data, HCC is the sixth most common type of cancer and the third leading cause of cancer-related mortality worldwide. Risk factors for HCC include the presence of the hepatitis B virus, hepatitis C virus, non-alcoholic fatty liver disease, and exposure to noxious agents, such as alcohol, or toxins, such as aflatoxin, which are considered preventable etiologies of HCC. Monitoring strategies are needed for patients at risk of developing HCC. There is a consensus on routine monitoring of cirrhotic patients due to definitive evidence of a significantly high rate of progression to HCC; however, the appropriate surveillance of patients with advanced fibrosis remains a topic of discussion. Nevertheless, adherence to a strict observation protocol is the cornerstone of early detection and treatment with curative options for patients with a high risk of developing HCC. This review examines prevention strategies, risk factors, and surveillance based on current guidelines. Kare Publishing 2022-01-09 /pmc/articles/PMC9138915/ /pubmed/35782375 http://dx.doi.org/10.14744/hf.2021.2021.0033 Text en © Copyright 2022 by Hepatology Forum - Available online at www.hepatologyforum.org https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Review - HCC prevention and surveillance
Kaya, Eda
Daniel Mazzolini, Guillermo
Yilmaz, Yusuf
Canbay, Ali
Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title_full Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title_fullStr Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title_full_unstemmed Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title_short Prevention of hepatocellular carcinoma and monitoring of high-risk patients
title_sort prevention of hepatocellular carcinoma and monitoring of high-risk patients
topic Review - HCC prevention and surveillance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138915/
https://www.ncbi.nlm.nih.gov/pubmed/35782375
http://dx.doi.org/10.14744/hf.2021.2021.0033
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