Different Effects of Valproic Acid on SLC12A2, SLC12A5 and SLC5A8 Gene Expression in Pediatric Glioblastoma Cells as an Approach to Personalised Therapy

Valproic acid (VPA) is a histone deacetylase inhibitor with sex-specific immunomodulatory and anticancer effects. This study aimed to investigate the effect of 0.5 and 0.75 mM VPA on NKCC1 (SLC12A2), KCC2 (SLC12A5) and SLC5A8 (SLC5A8) co-transporter gene expressions in pediatric PBT24 (boy’s) and SF...

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Detalles Bibliográficos
Autores principales: Damanskienė, Eligija, Balnytė, Ingrida, Valančiūtė, Angelija, Alonso, Marta Marija, Stakišaitis, Donatas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138981/
https://www.ncbi.nlm.nih.gov/pubmed/35625705
http://dx.doi.org/10.3390/biomedicines10050968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138981/
https://www.ncbi.nlm.nih.gov/pubmed/35625705
http://dx.doi.org/10.3390/biomedicines10050968

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