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A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage

Traumatic brain injury (TBI) remains a critical public health challenge. Although studies have found several prognostic factors for TBI, a useful early predictive tool for mortality has yet to be developed in the triage of the emergency room. This study aimed to use machine learning algorithms of ar...

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Autores principales: Tu, Kuan-Chi, Eric Nyam, Tee-Tau, Wang, Che-Chuan, Chen, Nai-Ching, Chen, Kuo-Tai, Chen, Chia-Jung, Liu, Chung-Feng, Kuo, Jinn-Rung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138998/
https://www.ncbi.nlm.nih.gov/pubmed/35624999
http://dx.doi.org/10.3390/brainsci12050612
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author Tu, Kuan-Chi
Eric Nyam, Tee-Tau
Wang, Che-Chuan
Chen, Nai-Ching
Chen, Kuo-Tai
Chen, Chia-Jung
Liu, Chung-Feng
Kuo, Jinn-Rung
author_facet Tu, Kuan-Chi
Eric Nyam, Tee-Tau
Wang, Che-Chuan
Chen, Nai-Ching
Chen, Kuo-Tai
Chen, Chia-Jung
Liu, Chung-Feng
Kuo, Jinn-Rung
author_sort Tu, Kuan-Chi
collection PubMed
description Traumatic brain injury (TBI) remains a critical public health challenge. Although studies have found several prognostic factors for TBI, a useful early predictive tool for mortality has yet to be developed in the triage of the emergency room. This study aimed to use machine learning algorithms of artificial intelligence (AI) to develop predictive models for TBI patients in the emergency room triage. We retrospectively enrolled 18,249 adult TBI patients in the electronic medical records of three hospitals of Chi Mei Medical Group from January 2010 to December 2019, and undertook the 12 potentially predictive feature variables for predicting mortality during hospitalization. Six machine learning algorithms including logistical regression (LR) random forest (RF), support vector machines (SVM), LightGBM, XGBoost, and multilayer perceptron (MLP) were used to build the predictive model. The results showed that all six predictive models had high AUC from 0.851 to 0.925. Among these models, the LR-based model was the best model for mortality risk prediction with the highest AUC of 0.925; thus, we integrated the best model into the existed hospital information system for assisting clinical decision-making. These results revealed that the LR-based model was the best model to predict the mortality risk in patients with TBI in the emergency room. Since the developed prediction system can easily obtain the 12 feature variables during the initial triage, it can provide quick and early mortality prediction to clinicians for guiding deciding further treatment as well as helping explain the patient’s condition to family members.
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spelling pubmed-91389982022-05-28 A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage Tu, Kuan-Chi Eric Nyam, Tee-Tau Wang, Che-Chuan Chen, Nai-Ching Chen, Kuo-Tai Chen, Chia-Jung Liu, Chung-Feng Kuo, Jinn-Rung Brain Sci Article Traumatic brain injury (TBI) remains a critical public health challenge. Although studies have found several prognostic factors for TBI, a useful early predictive tool for mortality has yet to be developed in the triage of the emergency room. This study aimed to use machine learning algorithms of artificial intelligence (AI) to develop predictive models for TBI patients in the emergency room triage. We retrospectively enrolled 18,249 adult TBI patients in the electronic medical records of three hospitals of Chi Mei Medical Group from January 2010 to December 2019, and undertook the 12 potentially predictive feature variables for predicting mortality during hospitalization. Six machine learning algorithms including logistical regression (LR) random forest (RF), support vector machines (SVM), LightGBM, XGBoost, and multilayer perceptron (MLP) were used to build the predictive model. The results showed that all six predictive models had high AUC from 0.851 to 0.925. Among these models, the LR-based model was the best model for mortality risk prediction with the highest AUC of 0.925; thus, we integrated the best model into the existed hospital information system for assisting clinical decision-making. These results revealed that the LR-based model was the best model to predict the mortality risk in patients with TBI in the emergency room. Since the developed prediction system can easily obtain the 12 feature variables during the initial triage, it can provide quick and early mortality prediction to clinicians for guiding deciding further treatment as well as helping explain the patient’s condition to family members. MDPI 2022-05-07 /pmc/articles/PMC9138998/ /pubmed/35624999 http://dx.doi.org/10.3390/brainsci12050612 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tu, Kuan-Chi
Eric Nyam, Tee-Tau
Wang, Che-Chuan
Chen, Nai-Ching
Chen, Kuo-Tai
Chen, Chia-Jung
Liu, Chung-Feng
Kuo, Jinn-Rung
A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title_full A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title_fullStr A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title_full_unstemmed A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title_short A Computer-Assisted System for Early Mortality Risk Prediction in Patients with Traumatic Brain Injury Using Artificial Intelligence Algorithms in Emergency Room Triage
title_sort computer-assisted system for early mortality risk prediction in patients with traumatic brain injury using artificial intelligence algorithms in emergency room triage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138998/
https://www.ncbi.nlm.nih.gov/pubmed/35624999
http://dx.doi.org/10.3390/brainsci12050612
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