Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77

Background: Pathogens or trauma-derived danger signals induced maturation and activation of plasmacytoid dendritic cells (pDCs) is a pivotal step in pDC-dependent host defense. Exposure of pDC to cardiometabolic disease-associated lipids and proteins may well influence critical signaling pathways, t...

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Detalles Bibliográficos
Autores principales: Christ, Anette, Goossens, Pieter G., Wijnands, Erwin, Jin, Han, Legein, Bart, Oth, Tammy, Isaacs, Aaron, Stoll, Monika, Vanderlocht, Joris, Lutgens, Esther, Daemen, Mat J. A. P., Zenke, Martin, Biessen, Erik A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139034/
https://www.ncbi.nlm.nih.gov/pubmed/35625889
http://dx.doi.org/10.3390/biomedicines10051152

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