Cargando…

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis

Acquired chemoresistance of tumor cells is an unwanted consequence of cancer treatment. Overcoming chemoresistance is particularly important for efficiently improving cancer therapies. Here, using multiple lines of evidence, we report the suppressive role of SERTAD1 in apoptosis/anoikis. Among vario...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Hai Anh, Vu, Son Hai, Jung, Samil, Lee, Beom Suk, Nguyen, Thi Ngoc Quynh, Lee, Hyojeong, Lee, Hye-gyeong, Myagmarjav, Davaajargal, Jo, Taeyeon, Choi, Yeongseon, Lee, Myeong-Sok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139069/ https://www.ncbi.nlm.nih.gov/pubmed/35625886 http://dx.doi.org/10.3390/biomedicines10051148

Ejemplares similares

Inhibitory role of TRIP-Br1 oncoprotein in anticancer drug-mediated programmed cell death via mitophagy activation
por: Jung, Samil, et al.
Publicado: (2022)

The regulation of insulin receptor/insulin-like growth factor 1 receptor ratio, an important factor for breast cancer prognosis, by TRIP-Br1
por: Nguyen, Thi Ngoc Quynh, et al.
Publicado: (2022)

Inhibitory Role of TRIP-Br1/XIAP in Necroptosis under Nutrient/Serum Starvation
por: Sandag, Zolzaya, et al.
Publicado: (2020)

Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis
por: Mongre, Raj Kumar, et al.
Publicado: (2020)

Prognostic and Clinicopathological Significance of SERTAD1 in Various Types of Cancer Risk: A Systematic Review and Retrospective Analysis
por: Mongre, Raj Kumar, et al.
Publicado: (2019)

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths
por: Jung, Samil, et al.
Publicado: (2018)

Enhancing the Thermo-Stability and Anti-Biofilm Activity of Alginate Lyase by Immobilization on Low Molecular Weight Chitosan Nanoparticles
por: Li, Shangyong, et al.
Publicado: (2019)

Biochemical Characterization of a New Oligoalginate Lyase and Its Biotechnological Application in Laminaria japonica Degradation
por: Li, Shangyong, et al.
Publicado: (2020)

The SERTAD protein Taranis plays a role in Polycomb-mediated gene repression
por: Dutta, Pranabananda, et al.
Publicado: (2017)

Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges
por: Li, Shangyong, et al.
Publicado: (2022)

REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis
por: Chen, Yunshang, et al.
Publicado: (2022)

Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells
por: Cheng, An-Chin, et al.
Publicado: (2019)

Cancer Resistance to Immunotherapy: Molecular Mechanisms and Tackling Strategies
por: Vu, Son Hai, et al.
Publicado: (2022)

Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway
por: Li, Jianxiong, et al.
Publicado: (2022)

Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma In Vitro and Xenograft Mice Model
por: Mongre, Raj Kumar, et al.
Publicado: (2019)

Sustainable biosynthesis of chemicals from methane and glycerol via reconstruction of multi‐carbon utilizing pathway in obligate methanotrophic bacteria
por: Le, Hoa Thi Quynh, et al.
Publicado: (2021)

A TiO(2)@MWCNTs nanocomposite photoanode for solar-driven water splitting
por: Le, Anh Quynh Huu, et al.
Publicado: (2022)

Sertad1 antagonizes iASPP function by hindering its entrance into nuclei to interact with P53 in leukemic cells
por: Qiu, Shaowei, et al.
Publicado: (2017)

Inhibitory Effect and Mechanism on Antiproliferation of Isoatriplicolide Tiglate (PCAC) from Paulownia Coreana
por: Jung, Samil, et al.
Publicado: (2012)

The relationship between effective personality and occupational health of lecturers: An empirical assessment in vietnam
por: Thanh, Nguyen Hai, et al.
Publicado: (2023)

An efficient enzyme-triggered controlled release system for colon-targeted oral delivery to combat dextran sodium sulfate (DSS)-induced colitis in mice
por: Li, Shangyong, et al.
Publicado: (2021)

Efficient Self-Assembly of mPEG End-Capped Porous Silica as a Redox-Sensitive Nanocarrier for Controlled Doxorubicin Delivery
por: Nguyen, Anh Khoa, et al.
Publicado: (2018)

Modelling in economic evaluation of mental health prevention: current status and quality of studies
por: Ha, Nguyen Thu, et al.
Publicado: (2022)

MicroRNA-92a Targets SERTAD3 and Regulates the Growth, Invasion, and Migration of Prostate Cancer Cells via the P53 Pathway
por: Zhang, Shuo, et al.
Publicado: (2020)

Optical Properties of Doxorubicin Hydrochloride Load and Release on Silica Nanoparticle Platform
por: Nguyen, Trong Nghia, et al.
Publicado: (2021)

Angelica gigas Nakai Has Synergetic Effects on Doxorubicin-Induced Apoptosis
por: Jeon, Yong-Joon, et al.
Publicado: (2018)

Alginate oligosaccharides can maintain activities of lysosomes under low pH condition
por: Park, Ra-Mi, et al.
Publicado: (2021)

Identifying Possible AChE Inhibitors from Drug-like Molecules via Machine Learning and Experimental Studies
por: Nguyen, Trung Hai, et al.
Publicado: (2022)

Perceptions of Dentists and Non-Professionals on Some Dental Factors Affecting Smile Aesthetics: A Study from Vietnam
por: Ngoc, Vo Truong Nhu, et al.
Publicado: (2020)

cis-Prenyltransferase interacts with a Nogo-B receptor homolog for dolichol biosynthesis in Panax ginseng Meyer
por: Nguyen, Ngoc Quy, et al.
Publicado: (2017)

Suppression of human breast tumors in NOD/SCID mice by CD44 shRNA gene therapy combined with doxorubicin treatment
por: Van Pham, Phuc, et al.
Publicado: (2012)

Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial—Lysosomal Axis
por: Kuk, Myeong Uk, et al.
Publicado: (2021)

A lysosome-targeted dextran-doxorubicin nanodrug overcomes doxorubicin-induced chemoresistance of myeloid leukemia
por: Zeng, Yunxin, et al.
Publicado: (2021)

Utility of skin testing in assessment of post-AZD1222 vaccine (AstraZeneca) allergic reactions: case series in Vietnam
por: Vu, Mai Thi, et al.
Publicado: (2021)

Understanding financial literacy and associated factors among adult population in a low-middle income country
por: Van Nguyen, Ha, et al.
Publicado: (2022)

Factors related to intracerebral haematoma in patients with aneurysmal subarachnoid haemorrhage in Vietnam: a multicentre prospective cohort study
por: Nguyen, Tuan Anh, et al.
Publicado: (2023)

Lung-protective mechanical ventilation for patients undergoing abdominal laparoscopic surgeries: a randomized controlled trial
por: Nguyen, Trung Kien, et al.
Publicado: (2021)

Validation of the accuracy of the modified World Federation of Neurosurgical Societies subarachnoid hemorrhage grading scale for predicting the outcomes of patients with aneurysmal subarachnoid hemorrhage
por: Nguyen, Tuan Anh, et al.
Publicado: (2023)

A novel single-point mutation of NEFH and biallelic SACS mutation presenting as intermediate form Charcot-Marie-Tooth: A case report in Vietnam
por: Truong, Anh Tuan, et al.
Publicado: (2022)

Income shock and food insecurity prediction Vietnam under the pandemic
por: Vu, Khoa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tl98okvfippramr09e11if8lqj