Construction of Multiscale Genome-Scale Metabolic Models: Frameworks and Challenges

Genome-scale metabolic models (GEMs) are effective tools for metabolic engineering and have been widely used to guide cell metabolic regulation. However, the single gene–protein-reaction data type in GEMs limits the understanding of biological complexity. As a result, multiscale models that add cons...

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Detalles Bibliográficos
Autores principales: Bi, Xinyu, Liu, Yanfeng, Li, Jianghua, Du, Guocheng, Lv, Xueqin, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139095/
https://www.ncbi.nlm.nih.gov/pubmed/35625648
http://dx.doi.org/10.3390/biom12050721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139095/
https://www.ncbi.nlm.nih.gov/pubmed/35625648
http://dx.doi.org/10.3390/biom12050721

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