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Construction of Multiscale Genome-Scale Metabolic Models: Frameworks and Challenges

Genome-scale metabolic models (GEMs) are effective tools for metabolic engineering and have been widely used to guide cell metabolic regulation. However, the single gene–protein-reaction data type in GEMs limits the understanding of biological complexity. As a result, multiscale models that add cons...

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Detalles Bibliográficos
Autores principales:	Bi, Xinyu, Liu, Yanfeng, Li, Jianghua, Du, Guocheng, Lv, Xueqin, Liu, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139095/ https://www.ncbi.nlm.nih.gov/pubmed/35625648 http://dx.doi.org/10.3390/biom12050721

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