Cargando…

Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study

Populations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobus, Magdalena, Żądzińska, Elżbieta, Sitek, Aneta, Pełka, Jacek, Rożniecki, Jacek J., Antoszewski, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139100/
https://www.ncbi.nlm.nih.gov/pubmed/35625007
http://dx.doi.org/10.3390/brainsci12050620
_version_ 1784714779734048768
author Kobus, Magdalena
Żądzińska, Elżbieta
Sitek, Aneta
Pełka, Jacek
Rożniecki, Jacek J.
Antoszewski, Bogusław
author_facet Kobus, Magdalena
Żądzińska, Elżbieta
Sitek, Aneta
Pełka, Jacek
Rożniecki, Jacek J.
Antoszewski, Bogusław
author_sort Kobus, Magdalena
collection PubMed
description Populations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present that light skin may modify the risk of Alzheimer’s and Parkinson’s diseases. However, the relationship between migraine and skin pigmentation has not been investigated yet. The objective of this study is to provide evidence of the relationship between skin pigmentation and migraine prevalence in adults. We examined a group of 148 adults (33 men, 115 women) with migraine and a control group of 107 adults (43 men, 64 women). Parameters of skin pigmentation (melanin index, erythema index, CIElab, and RGB scales) were measured using a DSM II Cortex Technology dermospectrophotometer. Risk of migraine in lightly pigmented adults was elevated. Individuals with a low melanin index had over 3-fold increased risk of migraine (women: OR 3.53, men: OR 3.73). Fair phototype, which results from lightly pigmented skin, was associated with migraine prevalence. Migraineurs should take extra care to protect their skin from the negative effects of solar radiation.
format Online
Article
Text
id pubmed-9139100
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91391002022-05-28 Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study Kobus, Magdalena Żądzińska, Elżbieta Sitek, Aneta Pełka, Jacek Rożniecki, Jacek J. Antoszewski, Bogusław Brain Sci Article Populations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present that light skin may modify the risk of Alzheimer’s and Parkinson’s diseases. However, the relationship between migraine and skin pigmentation has not been investigated yet. The objective of this study is to provide evidence of the relationship between skin pigmentation and migraine prevalence in adults. We examined a group of 148 adults (33 men, 115 women) with migraine and a control group of 107 adults (43 men, 64 women). Parameters of skin pigmentation (melanin index, erythema index, CIElab, and RGB scales) were measured using a DSM II Cortex Technology dermospectrophotometer. Risk of migraine in lightly pigmented adults was elevated. Individuals with a low melanin index had over 3-fold increased risk of migraine (women: OR 3.53, men: OR 3.73). Fair phototype, which results from lightly pigmented skin, was associated with migraine prevalence. Migraineurs should take extra care to protect their skin from the negative effects of solar radiation. MDPI 2022-05-10 /pmc/articles/PMC9139100/ /pubmed/35625007 http://dx.doi.org/10.3390/brainsci12050620 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kobus, Magdalena
Żądzińska, Elżbieta
Sitek, Aneta
Pełka, Jacek
Rożniecki, Jacek J.
Antoszewski, Bogusław
Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title_full Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title_fullStr Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title_full_unstemmed Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title_short Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
title_sort risk of migraine in europeans with low melanin levels—a population based case-control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139100/
https://www.ncbi.nlm.nih.gov/pubmed/35625007
http://dx.doi.org/10.3390/brainsci12050620
work_keys_str_mv AT kobusmagdalena riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy
AT zadzinskaelzbieta riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy
AT sitekaneta riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy
AT pełkajacek riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy
AT roznieckijacekj riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy
AT antoszewskibogusław riskofmigraineineuropeanswithlowmelaninlevelsapopulationbasedcasecontrolstudy