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De-Escalation of Anti-Tumor Necrosis Factor Alpha Agents and Reduction in Adverse Effects: A Systematic Review

Background: The long-term use of anti-TNF-α agents can lead to adverse effects, such as infections and immune-mediated cutaneous reactions. Whether de-escalation by dose reduction or interval lengthening reduces these adverse effects is uncertain. This systematic review aims to compare the incidence...

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Detalles Bibliográficos
Autores principales: Bouhuys, Marleen, Lexmond, Willem S., van Rheenen, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139158/
https://www.ncbi.nlm.nih.gov/pubmed/35625771
http://dx.doi.org/10.3390/biomedicines10051034