A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives

Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an important class of compounds for drug development; thus, they have attracted much attention. In the meantime, pyrazole derivatives have been synthesized as target structures and have demonstrated numerous biologica...

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Detalles Bibliográficos
Autores principales: Ebenezer, Oluwakemi, Shapi, Michael, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139179/
https://www.ncbi.nlm.nih.gov/pubmed/35625859
http://dx.doi.org/10.3390/biomedicines10051124
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author Ebenezer, Oluwakemi
Shapi, Michael
Tuszynski, Jack A.
author_facet Ebenezer, Oluwakemi
Shapi, Michael
Tuszynski, Jack A.
author_sort Ebenezer, Oluwakemi
collection PubMed
description Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an important class of compounds for drug development; thus, they have attracted much attention. In the meantime, pyrazole derivatives have been synthesized as target structures and have demonstrated numerous biological activities such as antituberculosis, antimicrobial, antifungal, and anti-inflammatory. This review summarizes the results of published research on pyrazole derivatives synthesis and biological activities. The published research works on pyrazole derivatives synthesis and biological activities between January 2018 and December 2021 were retrieved from the Scopus database and reviewed accordingly.
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spelling pubmed-91391792022-05-28 A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives Ebenezer, Oluwakemi Shapi, Michael Tuszynski, Jack A. Biomedicines Review Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an important class of compounds for drug development; thus, they have attracted much attention. In the meantime, pyrazole derivatives have been synthesized as target structures and have demonstrated numerous biological activities such as antituberculosis, antimicrobial, antifungal, and anti-inflammatory. This review summarizes the results of published research on pyrazole derivatives synthesis and biological activities. The published research works on pyrazole derivatives synthesis and biological activities between January 2018 and December 2021 were retrieved from the Scopus database and reviewed accordingly. MDPI 2022-05-12 /pmc/articles/PMC9139179/ /pubmed/35625859 http://dx.doi.org/10.3390/biomedicines10051124 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ebenezer, Oluwakemi
Shapi, Michael
Tuszynski, Jack A.
A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title_full A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title_fullStr A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title_full_unstemmed A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title_short A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives
title_sort review of the recent development in the synthesis and biological evaluations of pyrazole derivatives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139179/
https://www.ncbi.nlm.nih.gov/pubmed/35625859
http://dx.doi.org/10.3390/biomedicines10051124
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