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Comprehensive Analysis of Acquired Genetic Variants and Their Prognostic Impact in Systemic Mastocytosis

SIMPLE SUMMARY: Systemic mastocytosis (SM) is a clonal haematopoietic stem cell disease typically characterized by the expansion and accumulation of neoplastic mast cells carrying the activating KIT D816V as a driver mutation. Multilineage involvement of haematopoiesis by this KIT mutation, particul...

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Detalles Bibliográficos
Autores principales: González-López, Oscar, Muñoz-González, Javier I., Orfao, Alberto, Álvarez-Twose, Iván, García-Montero, Andrés C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139197/
https://www.ncbi.nlm.nih.gov/pubmed/35626091
http://dx.doi.org/10.3390/cancers14102487