Clinical Impact of Pathogenic Variants in DNA Damage Repair Genes beyond BRCA1 and BRCA2 in Breast and Ovarian Cancer Patients

SIMPLE SUMMARY: The clinical utility of positive findings in DNA damage-repair (DDR) genes BRCA1 and BRCA2 for the treatment of patients with breast or ovarian cancer is well established. However, multigene panel genetic testing for patients with breast and ovarian cancer now commonly includes DDR g...

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Autores principales: Espinel, Whitney, Champine, Marjan, Hampel, Heather, Jeter, Joanne, Sweet, Kevin, Pilarski, Robert, Pearlman, Rachel, Shane, Kate, Brock, Pamela, Westman, Judith A., Kipnis, Lindsay, Sotelo, Jilliane, Chittenden, Anu, Culver, Samantha, Stopfer, Jill E., Schneider, Katherine A., Sacca, Rosalba, Koeller, Diane R., Gaonkar, Shraddha, Vaccari, Erica, Kane, Sarah, Michalski, Scott T., Yang, Shan, Nielsen, Sarah M., Bristow, Sara L., Lincoln, Stephen E., Nussbaum, Robert L., Esplin, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139211/
https://www.ncbi.nlm.nih.gov/pubmed/35626031
http://dx.doi.org/10.3390/cancers14102426

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