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Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Non-small cell lung cancer (NSCLC) patients acquire resistance to tyrosine kinase inhibitors (TKIs) via EGFR mutations or overexpression of vascular endothelial growth factor receptor-2 (VEGFR-2). In this study, we elucidated the mechanism of EGFR-TKI resistance mediated by VEGF/VEGF...

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Detalles Bibliográficos
Autores principales: Osude, Chike, Lin, Leo, Patel, Meet, Eckburg, Adam, Berei, Joseph, Kuckovic, Adijan, Dube, Namrata, Rastogi, Aayush, Gautam, Shruti, Smith, Thomas J., Sreenivassappa, Shylendra B., Puri, Neelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139342/
https://www.ncbi.nlm.nih.gov/pubmed/35626731
http://dx.doi.org/10.3390/cells11101694