Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin

SIMPLE SUMMARY: Using a collection of publicly available drug screening resources, we identified different partners of genes associated with either sensitivity or resistance to 90 anti-cancer therapies. When subsequently applying these signatures to multiple datasets, we found that these predictive...

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Detalles Bibliográficos
Autores principales: Berthelet, Jean, Foroutan, Momeneh, Bhuva, Dharmesh D., Whitfield, Holly J., El-Saafin, Farrah, Cursons, Joseph, Serrano, Antonin, Merdas, Michal, Lim, Elgene, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Ernst, Matthias, Hollande, Frédéric, Anderson, Robin L., Pal, Bhupinder, Yeo, Belinda, Davis, Melissa J., Merino, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139442/
https://www.ncbi.nlm.nih.gov/pubmed/35626009
http://dx.doi.org/10.3390/cancers14102404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139442/
https://www.ncbi.nlm.nih.gov/pubmed/35626009
http://dx.doi.org/10.3390/cancers14102404

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