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Illuminating Medulloblastoma
Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University of Illinois at Chicago Library
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139469/ http://dx.doi.org/10.5210/jbc.v43i2.10280 |
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author | Rastan, Avesta Woolridge, Nicholas Dryer, Marc Daniels, Craig Taylor, Michael |
author_facet | Rastan, Avesta Woolridge, Nicholas Dryer, Marc Daniels, Craig Taylor, Michael |
author_sort | Rastan, Avesta |
collection | PubMed |
description | Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through the circulatory system. Understanding this new mechanism is critical for the development of therapies and to help affected families understand their child's disease. An educational 3D animation was developed to effectively disseminate this research to the scientific community and to educate physicians, researchers, and affected families about this disease. A story-driven narrative and emphasis on visual metaphor put the research in context by establishing why this research matters, what the future implications are, and how it is relevant to the audience. Additionally, various visual design strategies were implemented in order to increase memory retention and audience engagement. The final animation is the first visual resource that educates a lay audience on the two different mechanisms of medulloblastoma metastasis. |
format | Online Article Text |
id | pubmed-9139469 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | University of Illinois at Chicago Library |
record_format | MEDLINE/PubMed |
spelling | pubmed-91394692022-11-18 Illuminating Medulloblastoma Rastan, Avesta Woolridge, Nicholas Dryer, Marc Daniels, Craig Taylor, Michael J Biocommun Abstract Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through the circulatory system. Understanding this new mechanism is critical for the development of therapies and to help affected families understand their child's disease. An educational 3D animation was developed to effectively disseminate this research to the scientific community and to educate physicians, researchers, and affected families about this disease. A story-driven narrative and emphasis on visual metaphor put the research in context by establishing why this research matters, what the future implications are, and how it is relevant to the audience. Additionally, various visual design strategies were implemented in order to increase memory retention and audience engagement. The final animation is the first visual resource that educates a lay audience on the two different mechanisms of medulloblastoma metastasis. University of Illinois at Chicago Library 2019-11-27 /pmc/articles/PMC9139469/ http://dx.doi.org/10.5210/jbc.v43i2.10280 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License. |
spellingShingle | Abstract Rastan, Avesta Woolridge, Nicholas Dryer, Marc Daniels, Craig Taylor, Michael Illuminating Medulloblastoma |
title | Illuminating Medulloblastoma |
title_full | Illuminating Medulloblastoma |
title_fullStr | Illuminating Medulloblastoma |
title_full_unstemmed | Illuminating Medulloblastoma |
title_short | Illuminating Medulloblastoma |
title_sort | illuminating medulloblastoma |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139469/ http://dx.doi.org/10.5210/jbc.v43i2.10280 |
work_keys_str_mv | AT rastanavesta illuminatingmedulloblastoma AT woolridgenicholas illuminatingmedulloblastoma AT dryermarc illuminatingmedulloblastoma AT danielscraig illuminatingmedulloblastoma AT taylormichael illuminatingmedulloblastoma |