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Illuminating Medulloblastoma

Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through...

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Detalles Bibliográficos
Autores principales: Rastan, Avesta, Woolridge, Nicholas, Dryer, Marc, Daniels, Craig, Taylor, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Illinois at Chicago Library 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139469/
http://dx.doi.org/10.5210/jbc.v43i2.10280
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author Rastan, Avesta
Woolridge, Nicholas
Dryer, Marc
Daniels, Craig
Taylor, Michael
author_facet Rastan, Avesta
Woolridge, Nicholas
Dryer, Marc
Daniels, Craig
Taylor, Michael
author_sort Rastan, Avesta
collection PubMed
description Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through the circulatory system. Understanding this new mechanism is critical for the development of therapies and to help affected families understand their child's disease. An educational 3D animation was developed to effectively disseminate this research to the scientific community and to educate physicians, researchers, and affected families about this disease. A story-driven narrative and emphasis on visual metaphor put the research in context by establishing why this research matters, what the future implications are, and how it is relevant to the audience. Additionally, various visual design strategies were implemented in order to increase memory retention and audience engagement. The final animation is the first visual resource that educates a lay audience on the two different mechanisms of medulloblastoma metastasis.
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spelling pubmed-91394692022-11-18 Illuminating Medulloblastoma Rastan, Avesta Woolridge, Nicholas Dryer, Marc Daniels, Craig Taylor, Michael J Biocommun Abstract Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel research reveals that it can also spread through the circulatory system. Understanding this new mechanism is critical for the development of therapies and to help affected families understand their child's disease. An educational 3D animation was developed to effectively disseminate this research to the scientific community and to educate physicians, researchers, and affected families about this disease. A story-driven narrative and emphasis on visual metaphor put the research in context by establishing why this research matters, what the future implications are, and how it is relevant to the audience. Additionally, various visual design strategies were implemented in order to increase memory retention and audience engagement. The final animation is the first visual resource that educates a lay audience on the two different mechanisms of medulloblastoma metastasis. University of Illinois at Chicago Library 2019-11-27 /pmc/articles/PMC9139469/ http://dx.doi.org/10.5210/jbc.v43i2.10280 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Abstract
Rastan, Avesta
Woolridge, Nicholas
Dryer, Marc
Daniels, Craig
Taylor, Michael
Illuminating Medulloblastoma
title Illuminating Medulloblastoma
title_full Illuminating Medulloblastoma
title_fullStr Illuminating Medulloblastoma
title_full_unstemmed Illuminating Medulloblastoma
title_short Illuminating Medulloblastoma
title_sort illuminating medulloblastoma
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139469/
http://dx.doi.org/10.5210/jbc.v43i2.10280
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