Blockade LAT1 Mediates Methionine Metabolism to Overcome Oxaliplatin Resistance under Hypoxia in Renal Cell Carcinoma

SIMPLE SUMMARY: The transformation and mechanism of methionine metabolism of renal cell carcinoma (RCC) under a hypoxic microenvironment is not well understood as yet. This study illustrated that the reprogramming of methionine metabolism and the subsequent glutathione (GSH) synthesis were mediated...

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Detalles Bibliográficos
Autores principales: Xu, Qingwen, Liu, Yuxi, Sun, Wen, Song, Tiantian, Jiang, Xintong, Zeng, Kui, Zeng, Su, Chen, Lu, Yu, Lushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139506/
https://www.ncbi.nlm.nih.gov/pubmed/35626154
http://dx.doi.org/10.3390/cancers14102551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139506/
https://www.ncbi.nlm.nih.gov/pubmed/35626154
http://dx.doi.org/10.3390/cancers14102551

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