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Single-Cell Analyses of a Novel Mouse Urothelial Carcinoma Model Reveal a Role of Tumor-Associated Macrophages in Response to Anti-PD-1 Therapy

SIMPLE SUMMARY: Immune checkpoint inhibitors (ICI) have been standard care for advanced bladder cancer patients who fail or are not eligible for chemotherapy. There is an urgent need for preclinical models to study immunotherapy responses because the majority of patients with advanced bladder cancer...

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Detalles Bibliográficos
Autores principales: Xu, Dongbo, Wang, Li, Wieczorek, Kyle, Zhang, Yali, Wang, Zinian, Wang, Jianmin, Xu, Bo, Singh, Prashant K., Wang, Yanqing, Zhang, Xiaojing, Wu, Yue, Smith, Gary J., Attwood, Kristopher, Zhang, Yuesheng, Goodrich, David W., Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139541/
https://www.ncbi.nlm.nih.gov/pubmed/35626115
http://dx.doi.org/10.3390/cancers14102511