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Definition of the Prognostic Role of MGMT Promoter Methylation Value by Pyrosequencing in Newly Diagnosed IDH Wild-Type Glioblastoma Patients Treated with Radiochemotherapy: A Large Multicenter Study

SIMPLE SUMMARY: O(6)-methylguanine (O(6)-MeG)-DNA methyltransferase (MGMT) methylation status is a predictive factor for alkylating treatment efficacy and glioblastoma patients, and its prognostic role is still unclear. The quantitative pyrosequencing (PSQ) approach has proven to be feasible for MGM...

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Detalles Bibliográficos
Autores principales:	Caccese, Mario, Simonelli, Matteo, Villani, Veronica, Rizzato, Simona, Ius, Tamara, Pasqualetti, Francesco, Russo, Marco, Rudà, Roberta, Amoroso, Rosina, Bellu, Luisa, Bertorelle, Roberta, Cavallin, Francesco, Dipasquale, Angelo, Carosi, Mariantonia, Pizzolitto, Stefano, Cesselli, Daniela, Persico, Pasquale, Casini, Beatrice, Fassan, Matteo, Zagonel, Vittorina, Lombardi, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139569/ https://www.ncbi.nlm.nih.gov/pubmed/35626029 http://dx.doi.org/10.3390/cancers14102425

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