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One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021

During the COVID-19 pandemic, the lung ultrasound (LU) turned out to be a pivotal tool to study the lung involvement in the adult population, but the same was not well evaluated in children. We detected the LU patterns through an integrated approach with clinical–laboratory features in children hosp...

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Autores principales: Musolino, Anna Maria, Ferro, Valentina, Supino, Maria Chiara, Boccuzzi, Elena, Scateni, Simona, Sinibaldi, Serena, Cursi, Laura, Schingo, Paolo Maria Salvatore, Reale, Antonino, Campana, Andrea, Raponi, Massimiliano, Villani, Alberto, Tomà, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139579/
https://www.ncbi.nlm.nih.gov/pubmed/35626938
http://dx.doi.org/10.3390/children9050761
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author Musolino, Anna Maria
Ferro, Valentina
Supino, Maria Chiara
Boccuzzi, Elena
Scateni, Simona
Sinibaldi, Serena
Cursi, Laura
Schingo, Paolo Maria Salvatore
Reale, Antonino
Campana, Andrea
Raponi, Massimiliano
Villani, Alberto
Tomà, Paolo
author_facet Musolino, Anna Maria
Ferro, Valentina
Supino, Maria Chiara
Boccuzzi, Elena
Scateni, Simona
Sinibaldi, Serena
Cursi, Laura
Schingo, Paolo Maria Salvatore
Reale, Antonino
Campana, Andrea
Raponi, Massimiliano
Villani, Alberto
Tomà, Paolo
author_sort Musolino, Anna Maria
collection PubMed
description During the COVID-19 pandemic, the lung ultrasound (LU) turned out to be a pivotal tool to study the lung involvement in the adult population, but the same was not well evaluated in children. We detected the LU patterns through an integrated approach with clinical–laboratory features in children hospitalized for COVID-19 in relation to the temporal trend of the Italian epidemic. We conducted a retrospective study which took place at a pediatric tertiary hospital from 15 March 2020 to 15 March 2021. We compared the characteristics of the initial phase of the first COVID-19 year—in the spring and summer (15 March–30 September 2020)—and those of the second phase—in the autumn and winter (1 October 2020–15 March 2021). Twenty-eight patients were studied both in the first and in the second phase of the first COVID-19 year. The disease severity score (DSS) was significantly greater in the second phase (p = 0.015). In the second phase of the first COVID-19 year, we detected a more significant occurrence of the following LU features than in the first phase: the irregular pleural line (85.71% vs. 60.71%; p = 0.035), the B-lines (89.29% vs. 60%; p = 0.003) and the several but non-coalescent B-lines (89.29% vs. 60%; p = 0.003). The LU score correlated significantly with the DSS, with a moderate relationship (r = 0.51, p < 0.001). The combined clinical, laboratory and ultrasound approaches might be essential in the evaluation of pulmonary involvement in children affected by COVID-19 during different periods of the pandemic.
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spelling pubmed-91395792022-05-28 One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021 Musolino, Anna Maria Ferro, Valentina Supino, Maria Chiara Boccuzzi, Elena Scateni, Simona Sinibaldi, Serena Cursi, Laura Schingo, Paolo Maria Salvatore Reale, Antonino Campana, Andrea Raponi, Massimiliano Villani, Alberto Tomà, Paolo Children (Basel) Article During the COVID-19 pandemic, the lung ultrasound (LU) turned out to be a pivotal tool to study the lung involvement in the adult population, but the same was not well evaluated in children. We detected the LU patterns through an integrated approach with clinical–laboratory features in children hospitalized for COVID-19 in relation to the temporal trend of the Italian epidemic. We conducted a retrospective study which took place at a pediatric tertiary hospital from 15 March 2020 to 15 March 2021. We compared the characteristics of the initial phase of the first COVID-19 year—in the spring and summer (15 March–30 September 2020)—and those of the second phase—in the autumn and winter (1 October 2020–15 March 2021). Twenty-eight patients were studied both in the first and in the second phase of the first COVID-19 year. The disease severity score (DSS) was significantly greater in the second phase (p = 0.015). In the second phase of the first COVID-19 year, we detected a more significant occurrence of the following LU features than in the first phase: the irregular pleural line (85.71% vs. 60.71%; p = 0.035), the B-lines (89.29% vs. 60%; p = 0.003) and the several but non-coalescent B-lines (89.29% vs. 60%; p = 0.003). The LU score correlated significantly with the DSS, with a moderate relationship (r = 0.51, p < 0.001). The combined clinical, laboratory and ultrasound approaches might be essential in the evaluation of pulmonary involvement in children affected by COVID-19 during different periods of the pandemic. MDPI 2022-05-23 /pmc/articles/PMC9139579/ /pubmed/35626938 http://dx.doi.org/10.3390/children9050761 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Musolino, Anna Maria
Ferro, Valentina
Supino, Maria Chiara
Boccuzzi, Elena
Scateni, Simona
Sinibaldi, Serena
Cursi, Laura
Schingo, Paolo Maria Salvatore
Reale, Antonino
Campana, Andrea
Raponi, Massimiliano
Villani, Alberto
Tomà, Paolo
One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title_full One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title_fullStr One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title_full_unstemmed One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title_short One Year of Lung Ultrasound in Children with SARS-CoV-2 Admitted to a Tertiary Referral Children’s Hospital: A Retrospective Study during 2020–2021
title_sort one year of lung ultrasound in children with sars-cov-2 admitted to a tertiary referral children’s hospital: a retrospective study during 2020–2021
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139579/
https://www.ncbi.nlm.nih.gov/pubmed/35626938
http://dx.doi.org/10.3390/children9050761
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