Cargando…

Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons

Recent evidence suggests that SARS-CoV-2 hinders immune responses via dopamine (DA)-related mechanisms. Nonetheless, studies addressing the specific role of DA in the frame of SARS-CoV-2 infection are still missing. In the present study, we investigate the role of DA in SARS-CoV-2 replication along...

Descripción completa

Detalles Bibliográficos
Autores principales:	Limanaqi, Fiona, Zecchini, Silvia, Dino, Borana, Strizzi, Sergio, Cappelletti, Gioia, Utyro, Olga, Vanetti, Claudia, Garziano, Micaela, Saulle, Irma, Clerici, Mario, Biasin, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139638/ https://www.ncbi.nlm.nih.gov/pubmed/35626728 http://dx.doi.org/10.3390/cells11101691

Ejemplares similares

Saliva and Plasma Neutralizing Activity Induced by the Administration of a Third bnt162b2 Vaccine Dose
por: Garziano, Micaela, et al.
Publicado: (2022)

Salivary miRNA Profiles in COVID-19 Patients with Different Disease Severities
por: Saulle, Irma, et al.
Publicado: (2023)

Natural SARS-CoV-2 Infection Affects Neutralizing Activity in Saliva of Vaccinees
por: Garziano, Micaela, et al.
Publicado: (2022)

A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?
por: Saulle, Irma, et al.
Publicado: (2020)

MiRNA Profiling in Plasma and Placenta of SARS-CoV-2-Infected Pregnant Women
por: Saulle, Irma, et al.
Publicado: (2021)

Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms
por: Saulle, Irma, et al.
Publicado: (2021)

An Overview on ERAP Roles in Infectious Diseases
por: Saulle, Irma, et al.
Publicado: (2020)

SARS-CoV-2 vertical transmission during the first trimester of pregnancy in asymptomatic women
por: Fenizia, Claudio, et al.
Publicado: (2022)

Unlikely SARS-CoV-2 Transmission During Vaginal Delivery
por: Fenizia, Claudio, et al.
Publicado: (2021)

A Regulatory Polymorphism in HAVCR2 Modulates Susceptibility to HIV-1 Infection
por: Sironi, Manuela, et al.
Publicado: (2014)

Simplexviruses Successfully Adapt to Their Host by Fine-Tuning Immune Responses
por: Mozzi, Alessandra, et al.
Publicado: (2022)

UV and violet light can Neutralize SARS-CoV-2 Infectivity
por: Biasin, Mara, et al.
Publicado: (2022)

Pregnant Women Develop a Specific Immunological Long-Lived Memory Against SARS-COV-2
por: Fenizia, Claudio, et al.
Publicado: (2022)

The Modulation of Cholesterol Metabolism Is Involved in the Antiviral Effect of Nitazoxanide
por: Fenizia, Claudio, et al.
Publicado: (2021)

Immunological Characterization of HIV and SARS-CoV-2 Coinfected Young Individuals
por: Vanetti, Claudia, et al.
Publicado: (2021)

The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age
por: Vanetti, Claudia, et al.
Publicado: (2023)

Immunomodulatory activity of pidotimod administered with standard antibiotic therapy in children hospitalized for community-acquired pneumonia
por: Esposito, Susanna, et al.
Publicado: (2015)

Anti-Inflammatory Effects of Immunostimulation in Patients with COVID-19 Pneumonia
por: Santus, Pierachille, et al.
Publicado: (2021)

Severity of COVID-19 Patients Predicted by Serum Sphingolipids Signature
por: Torretta, Enrica, et al.
Publicado: (2021)

Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection
por: Saulle, Irma, et al.
Publicado: (2019)

Corrigendum: Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection
por: Saulle, Irma, et al.
Publicado: (2019)

High Expression of Antiviral and Vitamin D Pathway Genes Are a Natural Characteristic of a Small Cohort of HIV-1-Exposed Seronegative Individuals
por: Aguilar-Jimenez, Wbeimar, et al.
Publicado: (2017)

Thiazolides Elicit Anti-Viral Innate Immunity and Reduce HIV Replication
por: Trabattoni, Daria, et al.
Publicado: (2016)

Leishmania tarentolae as an Antigen Delivery Platform: Dendritic Cell Maturation after Infection with a Clone Engineered to Express the SARS-CoV-2 Spike Protein
por: Varotto-Boccazzi, Ilaria, et al.
Publicado: (2022)

Stimulation of PBMC and Monocyte-Derived Macrophages via Toll-Like Receptor Activates Innate Immune Pathways in HIV-Infected Patients on Virally Suppressive Combination Antiretroviral Therapy
por: Merlini, Esther, et al.
Publicado: (2016)

UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication
por: Biasin, Mara, et al.
Publicado: (2021)

SARS-CoV-2 Vaccination Effectiveness in Rituximab-Treated Patients Affected by Pemphigus Vulgaris
por: Fenizia, Claudio, et al.
Publicado: (2023)

Transcriptomic Analysis of HCN-2 Cells Suggests Connection among Oxidative Stress, Senescence, and Neuron Death after SARS-CoV-2 Infection
por: Valeri, Andrea, et al.
Publicado: (2021)

Olfactory bulb SARS‐CoV‐2 infection is not paralleled by the presence of virus in other central nervous system areas
por: Lopez, Gianluca, et al.
Publicado: (2021)

Vitamin D Receptor Gene Polymorphisms Are Associated with Obesity and Inflammosome Activity
por: Al-Daghri, Nasser M., et al.
Publicado: (2014)

SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in Pathogenesis
por: Gugliandolo, Agnese, et al.
Publicado: (2021)

No association of a risk variant for severe COVID-19 with HIV protection in three cohorts of highly exposed individuals
por: Sironi, Manuela, et al.
Publicado: (2022)

Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection
por: Sironi, Manuela, et al.
Publicado: (2015)

SARS-CoV-2 Exposed Mesenchymal Stromal Cell from Congenital Pulmonary Airway Malformations: Transcriptomic Analysis and the Expression of Immunomodulatory Genes
por: Valeri, Andrea, et al.
Publicado: (2021)

SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
por: Mozzi, Alessandra, et al.
Publicado: (2023)

Interdependency Between Autophagy and Synaptic Vesicle Trafficking: Implications for Dopamine Release
por: Limanaqi, Fiona, et al.
Publicado: (2018)

SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2
por: Fenizia, Claudio, et al.
Publicado: (2021)

The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery
por: Bandera, Alessandra, et al.
Publicado: (2018)

Ultraviolet C lamps for disinfection of surfaces potentially contaminated with SARS-CoV-2 in critical hospital settings: examples of their use and some practical advice
por: Lualdi, Manuela, et al.
Publicado: (2021)

The Effects of Amphetamine and Methamphetamine on the Release of Norepinephrine, Dopamine and Acetylcholine From the Brainstem Reticular Formation
por: Ferrucci, Michela, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tmr0dt1terddts8066i81qkf41