Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity

Lymph nodes are secondary lymphoid organs where T cells and B cells meet antigens to initiate adaptive immune responses. The anatomical and molecular cues direct the cell and fluid movements to ensure that the antigens can meet the right immune cells effectively 1, 2. Advanced 3D imaging techinques1 allowed the scientists to visualize the lymph nodes. However, Teaching lymph node architecture and immune cell dynamics at the cellular level is challenging due to the lack of visual teaching tools. Lymphatic Voyage is a widely accessible interactive 3D app designed as an educational tool to help instructors and graduate students.