Cargando…

Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity

Lymph nodes are secondary lymphoid organs where T cells and B cells meet antigens to initiate adaptive immune responses. The anatomical and molecular cues direct the cell and fluid movements to ensure that the antigens can meet the right immune cells effectively 1, 2. Advanced 3D imaging techinques1...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Li, Gregg, Lydia, Germain, Ronald N., Soloski, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Illinois at Chicago Library 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139832/
http://dx.doi.org/10.5210/jbc.v42i1.9185
_version_ 1784714952230043648
author Yao, Li
Gregg, Lydia
Germain, Ronald N.
Soloski, Mark J.
author_facet Yao, Li
Gregg, Lydia
Germain, Ronald N.
Soloski, Mark J.
author_sort Yao, Li
collection PubMed
description Lymph nodes are secondary lymphoid organs where T cells and B cells meet antigens to initiate adaptive immune responses. The anatomical and molecular cues direct the cell and fluid movements to ensure that the antigens can meet the right immune cells effectively 1, 2. Advanced 3D imaging techinques1 allowed the scientists to visualize the lymph nodes. However, Teaching lymph node architecture and immune cell dynamics at the cellular level is challenging due to the lack of visual teaching tools. Lymphatic Voyage is a widely accessible interactive 3D app designed as an educational tool to help instructors and graduate students.
format Online
Article
Text
id pubmed-9139832
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher University of Illinois at Chicago Library
record_format MEDLINE/PubMed
spelling pubmed-91398322022-11-18 Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity Yao, Li Gregg, Lydia Germain, Ronald N. Soloski, Mark J. J Biocommun Abstract Lymph nodes are secondary lymphoid organs where T cells and B cells meet antigens to initiate adaptive immune responses. The anatomical and molecular cues direct the cell and fluid movements to ensure that the antigens can meet the right immune cells effectively 1, 2. Advanced 3D imaging techinques1 allowed the scientists to visualize the lymph nodes. However, Teaching lymph node architecture and immune cell dynamics at the cellular level is challenging due to the lack of visual teaching tools. Lymphatic Voyage is a widely accessible interactive 3D app designed as an educational tool to help instructors and graduate students. University of Illinois at Chicago Library 2018-08-07 /pmc/articles/PMC9139832/ http://dx.doi.org/10.5210/jbc.v42i1.9185 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Abstract
Yao, Li
Gregg, Lydia
Germain, Ronald N.
Soloski, Mark J.
Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title_full Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title_fullStr Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title_full_unstemmed Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title_short Lymphatic Voyage: Communicating 4D Immune Cell Dynamics and Lymph Node Architecture Using WebGL-based Animation and Interactivity
title_sort lymphatic voyage: communicating 4d immune cell dynamics and lymph node architecture using webgl-based animation and interactivity
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139832/
http://dx.doi.org/10.5210/jbc.v42i1.9185
work_keys_str_mv AT yaoli lymphaticvoyagecommunicating4dimmunecelldynamicsandlymphnodearchitectureusingwebglbasedanimationandinteractivity
AT gregglydia lymphaticvoyagecommunicating4dimmunecelldynamicsandlymphnodearchitectureusingwebglbasedanimationandinteractivity
AT germainronaldn lymphaticvoyagecommunicating4dimmunecelldynamicsandlymphnodearchitectureusingwebglbasedanimationandinteractivity
AT soloskimarkj lymphaticvoyagecommunicating4dimmunecelldynamicsandlymphnodearchitectureusingwebglbasedanimationandinteractivity