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Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations
Breast cancer is the leading cause of cancer-related deaths in women. The aggressive breast cancer subtype is commonly linked to the genetic alterations in the TP53 tumor suppressor gene, predominantly the missense mutations. Robust experimental models are needed to gain better insights into these m...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139850/ https://www.ncbi.nlm.nih.gov/pubmed/35626649 http://dx.doi.org/10.3390/cells11101612 |