Cargando…

Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center

Pyomyositis (PM) is an infrequent but increasing bacterial infection of the skeletal muscle, with muscles of the pelvis and thigh frequently involved. The diagnosis is often challenging, especially when a deep muscle is affected. We present a single-center pediatric cohort affected by pelvic PM. A r...

Descripción completa

Detalles Bibliográficos
Autores principales: Abbati, Giulia, Abu Rumeileh, Sarah, Perrone, Anna, Galli, Luisa, Resti, Massimo, Trapani, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139856/
https://www.ncbi.nlm.nih.gov/pubmed/35626862
http://dx.doi.org/10.3390/children9050685
_version_ 1784714958045446144
author Abbati, Giulia
Abu Rumeileh, Sarah
Perrone, Anna
Galli, Luisa
Resti, Massimo
Trapani, Sandra
author_facet Abbati, Giulia
Abu Rumeileh, Sarah
Perrone, Anna
Galli, Luisa
Resti, Massimo
Trapani, Sandra
author_sort Abbati, Giulia
collection PubMed
description Pyomyositis (PM) is an infrequent but increasing bacterial infection of the skeletal muscle, with muscles of the pelvis and thigh frequently involved. The diagnosis is often challenging, especially when a deep muscle is affected. We present a single-center pediatric cohort affected by pelvic PM. A retrospective analysis was performed, including children admitted to Meyer Children’s Hospital between 2010 and 2020. Demographic, anamnestic, clinical, laboratory, radiological and management data were collected. Forty-seven patients (range 8 days–16.5 years, 66% males) were selected. Pain (64%), functional limitations (40%) and fever (38%) were the most common presenting symptoms; 11% developed sepsis. The median time to reach the diagnosis was 5 days (IQR 3–9). Staphylococcus aureus was the most common organism (30%), Methicillin-Resistant S aureus (MRSA) in 14%. PM was associated with osteomyelitis (17%), arthritis (19%) or both (45%). The infection was multifocal in 87% of children and determined abscesses in 44% (40% multiple). Pelvic MRI scan, including diffusion-weighted imaging (DWI), always showed abnormalities when performed. Clinical and laboratory findings in pelvic PM are unspecific, especially in infancy. Nevertheless, the infection may be severe, and the suspicion should be higher. MRI is the most useful radiological technique, and DWI sequence could reveal insidious infections.
format Online
Article
Text
id pubmed-9139856
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91398562022-05-28 Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center Abbati, Giulia Abu Rumeileh, Sarah Perrone, Anna Galli, Luisa Resti, Massimo Trapani, Sandra Children (Basel) Article Pyomyositis (PM) is an infrequent but increasing bacterial infection of the skeletal muscle, with muscles of the pelvis and thigh frequently involved. The diagnosis is often challenging, especially when a deep muscle is affected. We present a single-center pediatric cohort affected by pelvic PM. A retrospective analysis was performed, including children admitted to Meyer Children’s Hospital between 2010 and 2020. Demographic, anamnestic, clinical, laboratory, radiological and management data were collected. Forty-seven patients (range 8 days–16.5 years, 66% males) were selected. Pain (64%), functional limitations (40%) and fever (38%) were the most common presenting symptoms; 11% developed sepsis. The median time to reach the diagnosis was 5 days (IQR 3–9). Staphylococcus aureus was the most common organism (30%), Methicillin-Resistant S aureus (MRSA) in 14%. PM was associated with osteomyelitis (17%), arthritis (19%) or both (45%). The infection was multifocal in 87% of children and determined abscesses in 44% (40% multiple). Pelvic MRI scan, including diffusion-weighted imaging (DWI), always showed abnormalities when performed. Clinical and laboratory findings in pelvic PM are unspecific, especially in infancy. Nevertheless, the infection may be severe, and the suspicion should be higher. MRI is the most useful radiological technique, and DWI sequence could reveal insidious infections. MDPI 2022-05-09 /pmc/articles/PMC9139856/ /pubmed/35626862 http://dx.doi.org/10.3390/children9050685 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Abbati, Giulia
Abu Rumeileh, Sarah
Perrone, Anna
Galli, Luisa
Resti, Massimo
Trapani, Sandra
Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title_full Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title_fullStr Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title_full_unstemmed Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title_short Pelvic Pyomyositis in Childhood: Clinical and Radiological Findings in a Tertiary Pediatric Center
title_sort pelvic pyomyositis in childhood: clinical and radiological findings in a tertiary pediatric center
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139856/
https://www.ncbi.nlm.nih.gov/pubmed/35626862
http://dx.doi.org/10.3390/children9050685
work_keys_str_mv AT abbatigiulia pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter
AT aburumeilehsarah pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter
AT perroneanna pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter
AT galliluisa pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter
AT restimassimo pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter
AT trapanisandra pelvicpyomyositisinchildhoodclinicalandradiologicalfindingsinatertiarypediatriccenter