A Simple Flow Injection Analysis–Tandem Mass Spectrometry Method to Reduce False Positives of C5-Acylcarnitines Due to Pivaloylcarnitine Using Reference Ions †

Flow injection analysis–tandem mass spectrometry (FIA-TMS) has been applied in a first-tier test of newborn screening (NBS). Although isovalerylcarnitine (i-C5), which is a diagnostic indicator of isovaleric acidemia (IVA), is isobaric with pivaloylcarnitine (p-C5), 2-methylbutyrylcarnitine, and n-v...

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Detalles Bibliográficos
Autores principales: Hattori, Takanari, Notsu, Yoshitomo, Tanaka, Misa, Matsui, Miki, Iida, Tetsuo, Watanabe, Jun, Osawa, Yoshimitsu, Yamaguchi, Seiji, Yano, Shozo, Taketani, Takeshi, Kobayashi, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139860/
https://www.ncbi.nlm.nih.gov/pubmed/35626871
http://dx.doi.org/10.3390/children9050694

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