The History and Future of Basic and Translational Cell-Free DNA Research at a Glance

We discuss the early history of the structure of DNA and its involvement in gene structure as well as its mobility in and between cells and between tissues in the form of circulating cell-free DNA (cfDNA). This is followed by a view of the present status of the studies on cfDNA and clinical applicat...

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Autores principales: Gahan, Peter B., Schwarzenbach, Heidi, Anker, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139999/
https://www.ncbi.nlm.nih.gov/pubmed/35626347
http://dx.doi.org/10.3390/diagnostics12051192
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author Gahan, Peter B.
Schwarzenbach, Heidi
Anker, Philippe
author_facet Gahan, Peter B.
Schwarzenbach, Heidi
Anker, Philippe
author_sort Gahan, Peter B.
collection PubMed
description We discuss the early history of the structure of DNA and its involvement in gene structure as well as its mobility in and between cells and between tissues in the form of circulating cell-free DNA (cfDNA). This is followed by a view of the present status of the studies on cfDNA and clinical applications of circulating cell-free tumor DNA (ctDNA). The future developments and roles of ctDNA are also considered.
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spelling pubmed-91399992022-05-28 The History and Future of Basic and Translational Cell-Free DNA Research at a Glance Gahan, Peter B. Schwarzenbach, Heidi Anker, Philippe Diagnostics (Basel) Review We discuss the early history of the structure of DNA and its involvement in gene structure as well as its mobility in and between cells and between tissues in the form of circulating cell-free DNA (cfDNA). This is followed by a view of the present status of the studies on cfDNA and clinical applications of circulating cell-free tumor DNA (ctDNA). The future developments and roles of ctDNA are also considered. MDPI 2022-05-10 /pmc/articles/PMC9139999/ /pubmed/35626347 http://dx.doi.org/10.3390/diagnostics12051192 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gahan, Peter B.
Schwarzenbach, Heidi
Anker, Philippe
The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title_full The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title_fullStr The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title_full_unstemmed The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title_short The History and Future of Basic and Translational Cell-Free DNA Research at a Glance
title_sort history and future of basic and translational cell-free dna research at a glance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139999/
https://www.ncbi.nlm.nih.gov/pubmed/35626347
http://dx.doi.org/10.3390/diagnostics12051192
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