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Epigenetic-Like Stimulation of Receptor Expression in SSTR2 Transfected HEK293 Cells as a New Therapeutic Strategy

SIMPLE SUMMARY: Neuroendocrine tumors (NETs) expressing the somatostatin receptor subtype 2 (SSTR2) are promising targets for peptide receptor radionuclide therapy (PRRT) using the somatostatin analogue Lu-177-DOTATATE. Patients expressing low levels of SSTR2 do not benefit from PRRT. Therefore, an...

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Detalles Bibliográficos
Autores principales:	Kotzerke, Joerg, Buesser, Dorothee, Naumann, Anne, Runge, Roswitha, Huebinger, Lisa, Kliewer, Andrea, Freudenberg, Robert, Brogsitter, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140012/ https://www.ncbi.nlm.nih.gov/pubmed/35626117 http://dx.doi.org/10.3390/cancers14102513

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