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Concomitant Retinal Alterations in Neuronal Activity and TNFα Pathway Are Detectable during the Pre-Symptomatic Stage in a Mouse Model of Alzheimer’s Disease

The pre-symptomatic stage of Alzheimer’s disease (AD) is associated with increased amyloid-β (Aβ) precursor protein (APP) processing and Aβ accumulation in the retina and hippocampus. Because neuronal dysfunctions are among the earliest AD-related alterations, we asked whether they are already detec...

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Detalles Bibliográficos
Autores principales: Dinet, Virginie, Arouche-Delaperche, Louiza, Dégardin, Julie, Naud, Marie-Christine, Picaud, Serge, Krantic, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140134/
https://www.ncbi.nlm.nih.gov/pubmed/35626688
http://dx.doi.org/10.3390/cells11101650